The 28-year-old winger has not played for the Republic of Ireland since the 1-0 win over Slovakia more than 10 months ago. But he has made his comeback from a dislocated foot in the Newcastle side, and although he has yet to set St James' Park alight, it has been sufficient to persuade caretaker-manager Don Givens to include him in the squad for the Croke Park friendly.
Givens: "The return of Damien is a boost.
"There is no doubt he was sorely missed during the final stages of the Euro 2008 campaign."
Duff is joined in a 21-man squad Shay Given and ex-Toon defender Andy O'Brien.
The Bolton Wanderers player has not represented his country since the 5-2 defeat to Cyprus in October 2006.
REPUBLIC OF IRELAND SQUAD: Given (NEWCASTLE), Murphy (Scunthorpe), Doyle (Birmingham); Kelly (Birmingham), O'Shea (Man Utd), A O'Brien (Bolton), J O'Brien (Bolton), Kilbane (Wigan), Dunne (Man City), McShane (Sunderland); Carsley (Everton), A Reid (Charlton), S Reid (Blackburn), McGeady (Celtic), Hunt (Reading), Miller (Sunderland), Duff (NEWCASTLE); Keane (Tottenham), Doyle (Reading), Long (Reading), Murphy (Sunderland).