The France midfielder's stock rose after some impressive performances at Euro 2016 and has stated he does not want to remain at St James' Park and play in the Sky Bet Championship.
The club are yet to receive what they consider as an acceptable offer for Sissoko and it has been reported that he may even feature for Rafael Benitez's side against Huddersfield this weekend.
But the 26-year-old clearly has his heart set on a move away from Tyneside in the final weeks of the summer transfer window, with Spain his destination of choice.
"I hope Real will come for me, I'm still waiting," Sissoko told the BBC World Service.
"If Real Madrid are interested in you then of course you will be happy, but right now I am still a Newcastle player."