The 29-year-old flew back to England from his native Denmark following the funeral of his father, Bent, but he will not be involved in the squad at The Hawthorns.
Suggesting Hughton could, once again, put out a weakened side in the FA Cup, because he puts the competition down his list of priorities.
New signing Danny Simpson, who completed a permanent move to Tyneside on Wednesday evening after a successful loan spell, is a doubt after damaging an ankle on Monday evening.
Long-term absentee Joey Barton is still unavailable but the likes of Tim Krul, Tamas Kadar and Nile Ranger will once again come into contention.