The Nigeria international has missed the last four games with a groin problem but is now fit enough to resume.
Danny Guthrie and Joey Barton are suspended, while Mark Viduka and Habib Beye (both Achilles), Jonas Gutierrez (shoulder) and Jose Enrique are still missing.
Tottenham manager Juande Ramos may rest striker Roman Pavlyuchenko.
The cup holders are still seeking their first domestic victory of the season and Ramos has already used 21 players in five games. Midfielder Luka Modric is still struggling with a knee problem but has not been ruled out of the St James' Park clash..
Right-back Alan Hutton (foot) is a certain absentee but centre-backs Michael Dawson and Ledley King, who were both left out of the squad for the draw with Wigan on Sunday, could feature, along with on-loan Manchester United striker Fraizer Campbell.
NEWCASTLE (from): Given, Harper, Edgar, N'Zogbia, Taylor, Coloccini, Cacapa, Bassong, Tozer, Butt, Geremi, Duff, Gonzalez, Donninger, Owen, Xisco, Martins, Ameobi, Donaldson, Ranger, Danquah.
TOTTENHAM (from): Gomes, Bale, Gunter, Zokora, Bentley, Jenas, Woodgate, King, Dawson, Corluka, O'Hara, Lennon, Assou-Ekotto, Huddlestone, Campbell, Bent, Gilberto, Giovani, Pavlyuchenko, Modric, Cesar Sanchez.