The 61-year-old takes over a side sitting at the foot of the fourth tier, six points adrift of safety and with a minus 24 goal difference.
Moore, who was sacked by Tranmere in April of this year, replaces Paul Murray who was sacked in the wake of a shock 2-1 FA Cup defeat at home to minnows Blyth Spartans.
Murray failed to win a league match in his 45 days in charge at Victoria Park.