The Ivory Coast international is suspended after being sent off during the first half of last weekend's 1-1 derby draw at Sunderland.
However, manager Alan Pardew is likely to restore most of the men he left out of the starting line-up for last night's 1-0 Europa League victory over Club Brugge with Tim Krul, Danny Simpson, Fabricio Coloccini, Mike Williamson, Yohan Cabaye, Jonas Gutierrez, Hatem Ben Arfa, Shola Ameobi and Demba Ba all rested.
West Brom will check on the fitness of midfielder Claudio Yacob before finalising their side.
The Argentina international suffered a hamstring injury during last weekend's home reversal against Manchester City.
Skipper Chris Brunt (hamstring) and right-back Billy Jones (knee) have resumed training and could be in contention.
NEWCASTLE (from): Krul, Harper, Simpson, Tavernier, Ferguson, S. Taylor, Perch, Williamson, Santon, Cabaye, Gutierrez, Ben Arfa, Anita, Bigirimana, Marveaux, Obertan, Vuckic, Abeid, Amalfitano, Sammy Ameobi, Ba, Cisse, Shola Ameobi, Campbell.
WEST BROM (from): Foster, Myhill, Daniels, Jones, McAuley, Olsson, Tamas, Dawson, Jara Reyes, Popov, Ridgewell, Mulumbu, Yacob, Brunt, Dorrans, Morrison, El Ghanassy, Gera, Fortune, Odemwingie, Lukaku, Long, Rosenberg.