He has spent months recovering from Achilles trouble, and to add to United's problems, Jonas Gutierrez and Obafemi Martins are both highly unlikely to play against Hull.
Gutierrez faces tests on a shoulder injury sustained during Argentina's draw in Peru and initial reports suggested he had dislocated a shoulder in a collision with Paolo de le Haza.
But that was soon denied by the Argentine backroom team.
Joey Barton is another who will miss the game due to his ban, but at least La Liga imports Xisco and Ignacio Gonzalez are set to make their first appearances.
Brazilian centre-back Claudio Cacapa is likely to be available.